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Merck

55540

4-(Hydroxymercuri)benzoic acid sodium salt

≥95.0% (Hg)

Synonym(s):

p-Chloromercuribenzoate, p-Hydroxymercuribenzoic acid sodium salt, PCMB, Sodium 4-(hydroxymercurio)benzoate

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About This Item

Empirical Formula (Hill Notation):
C7H5HgNaO3
CAS Number:
138-85-2
Molecular Weight:
360.69
UNSPSC Code:
12352103
NACRES:
NA.25
PubChem Substance ID:
57651536
EC Number:
205-340-5
Beilstein/REAXYS Number:
6118796
MDL number:
MFCD00002527

Key Documents

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Product Name

4-(Hydroxymercuri)benzoic acid sodium salt, ≥95.0% (Hg)

InChI key

CBELQCYFTSHKPJ-UHFFFAOYSA-L

InChI

1S/C7H5O2.Hg.Na.H2O/c8-7(9)6-4-2-1-3-5-6;;;/h2-5H,(H,8,9);;;1H2/q;2*+1;/p-2

SMILES string

[Na+].O[Hg]c1ccc(cc1)C([O-])=O

assay

≥95.0% (Hg)

mp

≥300 °C

Quality Level

100

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Application

4-(Hydroxymercuri)benzoic acid is an organic mercurial compound that reacts via mercury-sulfur affinity with sulfhydryl groups in peptides, proteins and other molecules. PCMB may be used for the determination of sulfhydryl groups in proteins according to Boyer, by atomic absorption, and stopped-flow measurements, G. Castronuovo-Lepore et al.. It may be used for specific applications such as probing the active site of an enzyme such as cytochrome C oxidase. 4-(Hydroxymercuri)benzoic acid appeared mistakenly as p-chloromercuriobenzoate [PCMB] in earlier literature.

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

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Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
1403464V
1383409
1403464
1332224
1313236

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Jörg R Aschenbach et al.
American journal of physiology. Gastrointestinal and liver physiology, 296(5), G1098-G1107 (2009-03-07)
The present study investigated the significance of apical transport proteins for ruminal acetate absorption and their interaction with different anions. In anion competition experiments in the washed reticulorumen, chloride disappearance rate (initial concentration, 28 mM) was inhibited by the presence
Cristian Follmer et al.
European journal of biochemistry, 271(7), 1357-1363 (2004-03-20)
In this work we compared two plant ureases, jackbean urease (JBU) and embryo-specific soybean urease (SBU) and a bacterial (Bacillus pasteurii) urease, for kinetic parameters and other biological properties described recently for ureases that are independent of the ureolytic activity.
Mark D P Willcox et al.
Optometry and vision science : official publication of the American Academy of Optometry, 87(11), 839-846 (2010-09-08)
The purpose of this study was to investigate the effect of lens care products on short-term subjective and physiological performance silicone hydrogel lenses. Ten subjects wore either lotrafilcon B or galyfilcon A silicone hydrogel contact lenses soaked in a lens
Determination of protein thiol groups by atomic absorption spectrometry.
M Suzuki et al.
Analytical biochemistry, 32(1), 106-117 (1969-10-15)
Nadia Farhat et al.
Water research, 142, 227-235 (2018-06-11)
The bacterial growth potential is important to understand and manage bacterial regrowth-related water quality concerns. Bacterial growth potential depends on growth promoting/limiting compounds, therefore, nutrient availability is the key factor governing bacterial growth potential. Selecting proper tools for bacterial growth
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