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Merck

S4500

L-Serine

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
56-45-1
Molecular Weight:
105.09
PubChem Substance ID:
24899605
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.26
EC Number:
200-274-3
MDL number:
MFCD00064224
Beilstein/REAXYS Number:
1721404

Key Documents

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Product Name

L-Serine, ReagentPlus®, ≥99% (HPLC)

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

SMILES string

N[C@@H](CO)C(O)=O

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

color

white to off-white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

room temp

Quality Level

200

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Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.
Precursor of glycine by serine hydroxymethyltransferase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000516147
0000516150
0000516146
0000516150
0000516147

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Taiga Okumura et al.
Scientific reports, 9(1), 3520-3520 (2019-03-07)
Radiocaesium-bearing microparticles (CsMPs) composed of silicate glass were released by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. Since CsMPs contain a high concentration of radiocaesium, their dynamics and fate in the environment are urgent issues to be
Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
Nature Protocols, 8(9) (2003)
L-Serine in disease and development
Tom J. de Koning
Biochemistry, 371 (2003)
Taiga Okumura et al.
Scientific reports, 8(1), 9707-9707 (2018-06-28)
Radiocesium-bearing microparticles (CsPs) substantially made of silicate glass are a novel form of radiocesium emitted from the broken containment vessel of Fukushima Dai-ichi nuclear power plant. CsPs have a potential risk of internal radiation exposure caused by inhalation. Radiation-contaminated waste
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System , 4 (2007)
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