328650
Potassium tert-butoxide solution
1.0 M in THF
Synonym(s):
Potassium tert-butylate, Potassium-2-methylpropan-2-olate solution
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About This Item
Linear Formula:
(CH3)3COK
CAS Number:
Molecular Weight:
112.21
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3556712
form
liquid
Quality Level
reaction suitability
core: potassium
concentration
1.0 M in THF
density
0.902 g/mL at 25 °C
SMILES string
[K+].CC(C)(C)[O-]
InChI
1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
InChI key
LPNYRYFBWFDTMA-UHFFFAOYSA-N
General description
Potassium tert-butoxide solution is a strong non nucleophilic base. It is capable of deprotonating carbon and other Bronsted acids. Reagent solutions in tert-BuOh may be prepared by reacting anhydrous alcohol with potassium in nitrogen atmosphere.
Application
Potassium tert-butoxide solution(t-BuOK) can be used:
- As a catalyst for the interesterification of rapeseed oil with methyl acetate.
- To promote Sommelet–Hauser rearrangements of N-benzylic amino acid-derived ammonium ylides under mild conditions.
- As a metal-organic precursor in the synthesis of KNbO3 ferroelectric films by the chemical vapor deposition method.
- To prepare 3-potassiooxamethylpyridine catalyst.
- As a strong alkoxide base reagent.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
target_organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
4.3 - Hazardous materials which set free flammable gases upon contact with water
wgk
WGK 1
flash_point_f
-2.2 °F - closed cup
flash_point_c
-19 °C - closed cup
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Articles
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E Crespo-Corral et al.
Journal of chromatography. A, 1209(1-2), 22-28 (2008-10-01)
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