Skip to Content
Merck

Key Documents

View All Documentation

1.02143

Calcium phosphate

dried, EMPROVE® ESSENTIAL, Ph. Eur., BP, E 341 (iii)

Synonym(s):

Calcium phosphate, penta-Calcium hydroxide triphosphate, Calcium phosphate tribasic, Tricalcium orthophosphate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
Ca3O8P2
CAS Number:
7758-87-4
Molecular Weight:
310.18
UNSPSC Code:
12352302
E Number:
E341 (iii)
EC Index Number:
231-840-8
MDL number:
MFCD00015984
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

500

agency

BP, Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

solid

potency

>5000 mg/kg LD50, oral (Rat), >2000 mg/kg LD50, skin (Rabbit)

pH

6-8 (20 °C, 50 g/L in H2O, suspension)

mp

1670 °C

density

3.14 g/cm3 at 20 °C

application(s)

pharmaceutical
solid formulation

storage temp.

15-25°C

SMILES string

[Ca+2].[Ca+2].[Ca+2].[P](=O)([O-])([O-])[O-].[P](=O)([O-])([O-])[O-]

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

General description

To address challenges of solid formulation manufacturing, we have developed a comprehensive product portfolio to meet with your solid dosage needs in mind. Although solid dose formulations are one of the the most established dosage forms in the pharmaceutical market, the complexity of manufacturing final drug products is becoming more and more challenging. API stability, release kinetics and bioavailability limitations, such as low API solubility, are just a few of many critical obstacles on the way to the market.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium phosphate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, calcium phosphate is primarily used as a filler/binder.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Global Trade Item Number

SKUGTIN
1.02143.100004022536030081
1.02143.902604022536582641