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SYNPLE-H010

Reagent-cartridge Morpholine-2-spiro-(2-Pyr) (0)

Name: Reagent-cartridge Morpholine-2-spiro-(2-Pyr) (0)
Brand: SIAL

Synple

Synonym(s):

Synple 2

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About This Item

UNSPSC Code:

12161503

NACRES:

NA.22

MDL number:

MFCD32903606

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Properties

Quality Segment

100

reaction suitability

reaction type: Heterocycle Formation

parameter

up to 0.5 mmol scale

SMILES string

[s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C

InChI

1S/C28H38N4O7S/c1-17-24(40-16-30-17)19-7-5-18(6-8-19)14-29-26(37)21-13-20(33)15-32(21)27(38)25(28(2,3)4)31-22(34)9-11-39-12-10-23(35)36/h5-8,16,20-21,25,33H,9-15H2,1-4H3,(H,29,37)(H,31,34)(H,35,36)/t20-,21+,25-/m1/s1

InChI key

HVPZHRHEHKZOOJ-TYBLODHISA-N

Description

General description

Reagent-cartridge Morpholine-2-spiro-(2-Pyr) is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of a morpholine-pyrrolidine spirocycle from an aldehyde through the use of a SnAP reagent. The cartridge contains all necessary reagents for transforming the chosen aldehyde into a morpholine-pyrrolidine spirocycle.

Scale: up to 0.5 mmol
Heterocycle: Morpholine-pyrrolidine spirocycle
Compatible substrates: aldehyde

Cartridge contents:

Immobilized SnAP reagent
Cu catalyst (Cu(OTF)₂ and 2,6-lutidinium triflate)
SCX (for purification)
Silica (for purification)

Related Cartridges:

SYNPLE-H001Reagent-cartridge Morpholine
SYNPLE-H002Reagent-cartridge Oxazepane
SYNPLE-H004Reagent-cartridge 2-Methylmorpholine
SYNPLE-H005Reagent-cartridge Piperazine
SYNPLE-H006Reagent-cartridge Diazepane
SYNPLE-H007Reagent-cartridge 3-Methylmorpholine
SYNPLE-H011Reagent-cartridge Morpholine-2-spiro-(4-Pip)
SYNPLE-H090Reagent-cartridge 9-OMe-Benzoxazepane
SYNPLE-H091Reagent-cartridge 7-Br-9-OMe-Benzoxazepane

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
Safety - all chemicals are contained in the system, minimizing the user′s exposure
Set-up reaction in less than 5 minutes
Small footprint
Plug & Play system - simple installation
Reaction temperatures from 25 °C - 80 °C
Cartridges available for many different reactions
Prefilled with all required reagents
RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight

Legal Information

Product of Synple Chem AG

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H302,H411

pcodes

P264 - P270 - P273 - P301 + P312 - P391 - P501

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Synple Automatic Synthesizer & Reagent Cartridges

Discover Synple 2, an automated organic chemical synthesis system that allows researchers to have their products generated for them while reducing both human error and manual labor.