299537
Trifluoroacetic acid
≥99%, for protein sequencing
Synonym(s):
TFA
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About This Item
Linear Formula:
CF3COOH
CAS Number:
Molecular Weight:
114.02
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-929-3
Beilstein/REAXYS Number:
742035
MDL number:
Assay:
≥99%
Form:
liquid
vapor density
3.9 (vs air)
Quality Segment
vapor pressure
97.5 mmHg ( 20 °C)
type
for protein sequencing
assay
≥99%
form
liquid
impurities
<0.05% water
evapn. residue
<0.005%
refractive index
n
pH
1 (20 °C, 10 g/L)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
solubility
water: soluble 10.000 g/L
density
1.489 g/mL at 20 °C (lit.)
SMILES string
OC(C(F)(F)F)=O
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
General description
Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination.
- High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues.
- Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR.
- Ensures Integrity of Genetic Material: Promotes reliable and reproducible results.
- Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency.
Trifluoroacetic acid is a naturally occurring organic solvent and biodegradable by microbial action. It can also be used as a catalyst for various organic transformations, including solvolysis, rearrangements, reductions, oxidations, and trifluoromethylation.
Application
Trifluoroacetic acid can be used as a solvent in the:
- Mass spectrometry for protein identification.
- Microwave-irradiated bromination of isoxazoles and pyrazoles with N-bromosuccinimide to synthesize mono-brominated isoxazoles and pyrazoles.
- Lewis acid-catalyzed 6-endo-digcyclization of 2-(2-arylethynyl)heteroaryl esters to heterocyclic lactones.
- Electrospinning of cellulose acetate to prepare the corresponding nanofibrous membranes.
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Danger
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
No data available
flash_point_c
No data available
supp_hazards
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1A
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