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T8691

Taurine

Name: Taurine
Brand: SIGMA

suitable for cell culture, BioXtra, meets USP testing specifications

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:

NH₂CH₂CH₂SO₃H

CAS Number:

107-35-7

Molecular Weight:

125.15

NACRES:

NA.26

PubChem Substance ID:

24900552

UNSPSC Code:

12352209

EC Number:

203-483-8

MDL number:

MFCD00008197

Beilstein/REAXYS Number:

1751215

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Properties

Product Name

Taurine, suitable for cell culture, meets USP testing specifications

agency

meets USP testing specifications

product line

BioXtra

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

>300 °C (lit.)

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

rat ... Ppm1a(24666)

Description

Application

Taurine has been used:

as a component of cardiomyocyte dissociation solution
as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
as a constituent of low Ca²⁺ solution employed in preparation of collagenase B solution for colony dissociation into single cells
to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
as a component of culture media for derivation of cornea organoids

Biochem/physiol Actions

Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.

Non-selective endogenous agonist at glycine receptors.

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Articles

BPA가 없는 배양 배지를 위한 초순수

Milli-Q^® 시스템의 초순수는 BPA가 없는 것으로 드러나 발생학 연구에 적합하여 내분비 교란 물질의 간섭을 최소화합니다.

Ultrapure Water for BPA free Cell Culture Media in Embryology

See data showing Milli-Q^® ultrapure water suitability for preparing BPA-free culture media in reproductive biology research.

Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells

Zanella F and Sheikh F

Methods in Molecular Biology, 147-162 (2014)

The Effect of Various Concentrations of Taurine during In vitro Fertilization on the Development of Bovine Embryos Fertilized with Spermatozoa from Three Different Bulls

Tsuzuki Y, et al.

Asian-Australasian Journal of Animal Sciences (2010)

Scalable expansion of human pluripotent stem cells in suspension culture

Zweigerdt R, et al.

Nature Protocols, 6(5), 689-689 (2011)

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