AP130P
Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate
0.8 mg/mL, Chemicon®
동의어(들):
Goat Anti-Mouse IgG Antibody
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제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
peroxidase conjugate
Clone:
polyclonal
Application:
ELISA, WB
Citations:
58
biological source
goat
Quality Segment
conjugate
peroxidase conjugate
antibody form
F(ab′)2 fragment of affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
concentration
0.8 mg/mL
technique(s)
ELISA: suitable, western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
General description
Immunoglobulin G (IgG) is the most abundant immunoglobulin in the human serum. IgM constitutes 5-10% of total serum immunoglobulins. These immunoglobulins comprise four polypeptide chains with two heavy (H) chains and two light (L) chains. These polypeptide chains are inter-linked by disulfide bonds. IgM is a highly conserved antibody in vertebrates. IgM exists as a pentamer. Both IgG and IgM are secreted by B cells.
Application
Biochem/physiol Actions
IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). It also aids in the activation of the classical pathway of the complement system. IgG neutralizes virus particles and toxins. IgM, an antibody that is expressed early during an immune response, aids in engulfing apoptotic cells. It exhibits polyreactive and autoreactive functionality. IgM induces tissue homeostasis by mediating the clearance of tissue-based molecules. Lower levels of IgM in serum are associated with increased autoimmune response and a higher risk of developing infections.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable