04-259
Anti-19S regulator non-ATPase subunit S5a/Rpn10 Antibody, clone S5a-18
clone S5a-18, Upstate®, from mouse
동의어(들):
S5a
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
S5a-18, monoclonal
Application:
IP, WB
Citations:
34
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S5a-18, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PSMD4(5710)
General description
41 kDa
Rpn10 (S5a) is a non-ATPase subunit of the 19S regulatory complex of the 26s proteasome. Subunit Rpn10 (S5a) of the 26S proteasome was originally identified as a protein capable of binding poly-ubiquitin chains of four or more ubiquitins, in the absence of other 26S proteasome subunits.
Immunogen
Full length human recombinant Rpn10 protein.
Application
Detect 19S regulator non-ATPase subunit S5a/Rpn10 using this Anti-19S regulator non-ATPase subunit S5a/Rpn10 Antibody, clone S5a-18 validated for use in IP & WB.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
Ubiquitin & Ubiquitin Metabolism
Biochem/physiol Actions
Recognizes 19S regulator non-ATPase subunit S5a/Rpn10.
Physical form
100 µL of purified immunoglobulin in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Format: Purified
Preparation Note
Stable for 1 year at -20°C from date of shipment for up to 12 months.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
저장 등급
12 - Non Combustible Liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Kylie J Walters et al.
Biochemistry, 41(6), 1767-1777 (2002-02-06)
The 26S proteasome is essential for the proteolysis of proteins that have been covalently modified by the attachment of polyubiquitinated chains. Although the 20S core particle performs the degradation, the 19S regulatory cap complex is responsible for recognition of polyubiquitinated
Purification of poly-ubiquitinated proteins by S5a-affinity chromatography
Layfield, R, et al
Proteomics, 1, 773-777 (2001)
Anna J Slezak et al.
ACS central science, 8(10), 1435-1446 (2022-11-01)
Immune stimulating agents like Toll-like receptor 7 (TLR7) agonists induce potent antitumor immunity but are limited in their therapeutic window due to off-target immune activation. Here, we developed a polymeric delivery platform that binds excess unpaired cysteines on tumor cell
C R Wilkinson et al.
Nature cell biology, 3(10), 939-943 (2001-10-05)
The UBA domain is a motif found in a variety of proteins, some of which are associated with the ubiquitin-proteasome system. We describe the isolation of a fission-yeast gene, mud1+, which encodes a UBA domain containing protein that is able
Yuqing Lei et al.
STAR protocols, 3(1), 101035-101035 (2022-01-04)
Palmitoylation is a special kind of lipid modification that targets proteins to membranes. This protocol introduces the acyl-biotin exchange (ABE) assay to determine the palmitoylation of protein cysteines in yeast. Palmitoylation is exchanged by biotinylated compounds so that the palmitoyl proteins
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 04-259 | 04053252515262 |
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