04-293
Anti-phospho-erbB2 (Thr686) Antibody, clone 7F8
clone 7F8, Upstate®, from mouse
동의어(들):
NEU, NGL, HER2, TKR1, HER-2, c-erb B2
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
7F8, monoclonal
Species reactivity:
mouse, human, canine
Application:
ELISA
western blot
western blot
Technique(s):
ELISA: suitable
western blot: suitable
western blot: suitable
Citations:
5
Uniprot accession no.:
제품 이름
Anti-phospho-erbB2 (Thr686) Antibody, clone 7F8, clone 7F8, Upstate®, from mouse
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
7F8, monoclonal
species reactivity
mouse, human, canine
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr686)
Quality Level
Gene Information
human ... ERBB2(2064)
mouse ... Erbb2(13866)
Analysis Note
Control
Positive Antigen Control: Catalog #12-302, EGF-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-302, EGF-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Routinely evaluated by immunoblot.
Application
Anti-phospho-erbB2 (Thr686) Antibody, clone 7F8 is an antibody against phospho-erbB2 (Thr686) for use in ELISA & WB.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Kinases & Phosphatases
Growth Factors & Receptors
Kinases & Phosphatases
Biochem/physiol Actions
Recognizes phosphorylated erbB2 on Threonine 686
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
180 kDa
Immunogen
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Thr 686 in human erbB2
Physical form
Format: Purified
In 1 mL of PBS containing 0.09% sodium azide, PEG, sucrose and 50% glycerol.
Subsequent thiophilic adsorption and size exclusion chromatography
Preparation Note
2 years at -20°C from date of shipment. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
저장 등급
10 - Combustible liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Human cancer cells exhibit protein kinase C-dependent c-erbB-2 transmodulation that correlates with phosphatase sensitivity and kinase activity
Ouyang, X, et al
The Journal of Biological Chemistry, 271, 21786-21792 (1996)
X Ouyang et al.
Carcinogenesis, 19(11), 2013-2019 (1998-12-17)
Tumour cell growth may be accelerated by protein kinase C (PKC) agonists such as phorbol esters and receptor tyrosine kinases, but receptor tyrosine kinases are in turn desensitized to growth factors by PKC agonists. To clarify this apparent PKC bifunctionality
Natasha M Bourgeois et al.
Frontiers in cellular and infection microbiology, 14, 1264525-1264525 (2024-04-08)
Dengue is an arboviral disease causing severe illness in over 500,000 people each year. Currently, there is no way to constrain dengue in the clinic. Host kinase regulators of dengue virus (DENV) infection have the potential to be disrupted by
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 04-293 | 04053252472848 |
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.