05-545
Anti-PP2A Antibody, C subunit, clone 7A6
culture supernatant, clone 7A6, Upstate®
동의어(들):
Anti-NEDLBA, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
7A6, monoclonal
Application:
IP, WB
Citations:
26
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
7A6, monoclonal
species reactivity
mouse, Saccharomyces cerevisiae, human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PPP2CA(5515)
General description
36 kDa
Immunogen
peptide (C-bARRTPDYFL) corresponding to amino acids 302-309 of human PP2A catalytic subunit
Application
Anti-PP2A Antibody, C subunit, clone 7A6 detects level of PP2A & has been published & validated for use in IP & WB.
Research Category
Signaling
Neuroscience
Signaling
Neuroscience
Research Sub Category
Kinases & Phosphatases
Neurodegenerative Diseases
Kinases & Phosphatases
Neurodegenerative Diseases
Biochem/physiol Actions
Recognizes the catalytic subunit of PP2A.
Physical form
Cell culture supernatant containing 30% glycerol and 0.05% sodium azide as a preservative.
Unpurified
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysates from A431 cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Modeling initiation of Ewing sarcoma in human neural crest cells.
von Levetzow, C; Jiang, X; Gwye, Y; von Levetzow, G; Hung, L; Cooper, A; Hsu, JH; Lawlor, ER
Testing null
Regulation of L-type calcium channel and delayed rectifier potassium channel activity by p21-activated kinase-1 in guinea pig sinoatrial node pacemaker cells.
Ke, Y; Lei, M; Collins, TP; Rakovic, S; Mattick, PA; Yamasaki, M; Brodie, MS; Terrar, DA; Solaro, RJ
Circulation Research null
Chang Y Guo et al.
The Journal of biological chemistry, 277(7), 4839-4844 (2001-11-28)
Ionizing radiation (IR) is known to activate multiple cell cycle checkpoints that are thought to enhance the ability of cells to respond to DNA damage. Protein phosphatase 2A (PP2A) has been implicated in IR-induced activation of checkpoints; therefore, Jurkat cells
Loss of protein phosphatase 2A expression correlates with phosphorylation of DP-1 and reversal of dysplasia through differentiation in a conditional mouse model of cancer progression.
Maddalena T Tilli, Shawnte L Hudgins, M Silvina Frech, Ewa D Halama, Jean-Pierre Renou et al.
Cancer Research null
N Begum et al.
The Journal of biological chemistry, 271(49), 31166-31171 (1996-12-06)
In this study, we examined the mechanism of recently reported inactivation of protein phosphatase-2A (PP-2A) by insulin (Srinivasan, M., and Begum, N. (1994) J. Biol. Chem. 269, 12514-12520) and its counter-regulation by cAMP agonists. Exposure of L6 myotubes to insulin
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 05-545 | 04053252281099 |
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