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Merck

07-315

Anti-SGK1 Antibody

Upstate®, from rabbit

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunoprecipitation (IP)
western blot
Species reactivity:
human, rat
Citations:
32
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
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제품 이름

Anti-SGK1 Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SGK1(6446)

Analysis Note

Control
Rat 2 cell lysate
routinely evaluated by immunoblot on RIPA lysates from A431 and Rat 2 cells

Application

Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
This Anti-SGK1 Antibody is validated for use in IP, WB for the detection of SGK1.

Biochem/physiol Actions

Recognizes SGK1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

~50 kDa

Immunogen

peptide corresponding to amino acids 399-412 (C-GKSPDSVLVTASVK) of human SGK1

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1027

Physical form

Format: Purified
Immunoaffinity Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide and 1.75mg/ml BSA before the addition of glycerol to 30%
Protein A purified

Preparation Note

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Melissa L Vadnais et al.
Biology of reproduction, 89(5), 127-127 (2013-09-06)
Sperm motility encompasses a wide range of events involving epididymal maturation and activation of biochemical pathways, most notably cyclic AMP (cAMP)-protein kinase A (PKA) activation. Following the discovery of guanine-nucleotide exchange factors (RAPGEFs), also known as exchange proteins activated by
Lucia D'Antona et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 35(5), 2006-2018 (2015-04-15)
Published observations on serum and glucocorticoid regulated kinase 1 (Sgk1) knockout murine models and Sgk1-specific RNA silencing in the RKO human colon carcinoma cell line point to this kinase as a central player in colon carcinogenesis and in resistance to
C Filion et al.
The Journal of pathology, 217(1), 83-93 (2008-10-16)
The NR4A3 nuclear receptor is implicated in the development of extraskeletal myxoid chondrosarcoma (EMC), primitive sarcoma unrelated to conventional chondrosarcomas, through a specific fusion with EWSR1 resulting in an aberrant fusion protein that is thought to disrupt the transcriptional regulation
Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor.
Wang, D; Zhang, H; Lang, F; Yun, CC
American Journal of Physiology. Cell Physiology null
SGK protein kinase facilitates the expression of long-term potentiation in hippocampal neurons
Ma, Yun L, et al
Learning & Memory, 13, 114-118 null

국제 무역 품목 번호

SKUGTIN
07-31504053252326271

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