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Merck

07-373

Anti-acetyl-Histone H2B Antibody

Upstate®, from rabbit

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
13
기술 서비스
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도움 문의
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도움 문의

biological source

rabbit

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

acetylation (Lys5,Lys12,Lys15,Lys20)

Quality Level

Gene Information

human ... H2BC1(255626)

General description

15 kDa

Immunogen

Synthetic peptide in which there is an acetyl-lysine at residues 5, 12, 15 and 20 of human Histone H2B

Application

Detect acetyl-Histone H2B also known as Histone H2B with Anti-acetyl-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Biochem/physiol Actions

acetylated Histone H2B

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot in sodium butyrate treated, acid extracted proteins from HeLa cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

10 - Combustible liquids

wgk

WGK 1


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus.
Bousiges, O; Vasconcelos, AP; Neidl, R; Cosquer, B; Herbeaux, K; Panteleeva, I; Loeffler et al.
Neuropsychopharmacology null
Estelle Schueller et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 33, 101-116 (2020-02-15)
Memory impairment is the main feature of Alzheimer's disease (AD). Initial impairments originate in the temporal lobe area and propagate throughout the brain in a sequential manner. Epigenetic mechanisms, especially histone acetylation, regulate plasticity and memory processes. These may be
Kelly L West et al.
Immunity, 23(2), 203-212 (2005-08-23)
V(D)J recombination is a tightly controlled process of somatic recombination whose regulation is mediated in part by chromatin structure. Here, we report that RAG2 binds directly to the core histone proteins. The interaction with histones is observed in developing lymphocytes
Snehajyoti Chatterjee et al.
EMBO molecular medicine, 10(11) (2018-10-03)
Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of
A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.
Chatterjee, S; Mizar, P; Cassel, R; Neidl, R; Selvi, BR; Mohankrishna, DV; Vedamurthy et al.
The Journal of Neuroscience null

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SKUGTIN
07-37304053252273292

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