14-418
p300, HAT Domain
Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352202
NACRES:
NA.41
eCl@ss:
32160405
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
Mw 100 kDa
biological source
human
recombinant
expressed in E. coli
mol wt
Mw 100 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (histone acetyltransferase (HAT))
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Quality Level
Gene Information
human ... EP300(2033)
General description
Product Source: Expressed in E. coli.
Application
Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.
Preparation Note
-20°C for up to 6 months from the date of receipt.
Analysis Note
Routinely evaluated by HAT Assay.
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Specific Activity: 1 Unit is defined as the transfer of 1nmol of [3H]-acetate/minute to acid-extracted histones.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
저장 등급
10 - Combustible liquids
wgk
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.
Weibin Wang,Kewu Pan,Yifan Chen,Chunyin Huang,Xiaowei Zhang
Nucleic Acids Research null
A Giordano et al.
Journal of cellular physiology, 181(2), 218-230 (1999-09-25)
p300 and CBP are highly related nuclear proteins, which have been implicated in transcriptional responses to disparate extracellular and intracellular signals. There are at least two very good reasons for which p300 and CBP have attracted the attention of the
R L Schiltz et al.
The Journal of biological chemistry, 274(3), 1189-1192 (1999-01-09)
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between hyperacetylated chromatin and transcriptional activation. We have determined the core histone residues acetylated in vitro by recombinant p300 and PCAF within mononucleosomes. p300 specifically acetylates
Junhui Xue et al.
Cancer letters, 471, 12-26 (2019-12-08)
Alpha-fetoprotein (AFP) is a well-established biomarker for hepatocellular carcinoma (HCC). Here, we investigated the acetylation state of AFP in vivo. AFP acetylation was regulated by the acetyltransferase CBP and the deacetylase SIRT1. Acetylation of AFP at lysines 194, 211, and
Dennis Shin-Shian Hsu et al.
Cancer cell, 26(4), 534-548 (2014-10-15)
Snail is primarily known as a transcriptional repressor that induces epithelial-mesenchymal transition by suppressing adherent proteins. Emerging evidence suggests that Snail can act as an activator; however, the mechanism and biological significance are unclear. Here, we found that CREB-binding protein
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 14-418 | 04053252470424 |
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