14-902-M
AMPK (α2, β1, γ1) Protein, active, 10 µg
Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
biological source
human
Quality Segment
recombinant
expressed in E. coli
product line
Upstate®
specific activity
(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
mol wt
Mw 30 kDa (AMPKβ1), Mw 38 kDa (AMPKγ1), Mw 63 kDa (AMPKα2)
purified by
(Ni2+/NTA-agarose)
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
accession no.
(Function: Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5′-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. ), NM_006252
UniProt accession no.
relevant disease(s)
diabetes; obesity; metabolic disorders
Gene Information
human ... PRKAA2(5563), PRKAB1(5563)
General description
Application
Metabolism
Apoptosis & Cancer
Diabetes
Obesity
Metabolic Disorders
Biochem/physiol Actions
Packaging
Physical form
Preparation Note
Analysis Note
Other Notes
Legal Information
Disclaimer
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
저장 등급
10 - Combustible liquids
wgk
WGK 1
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.