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Merck

AB15708A4

Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate | AB15708A4

from rabbit, ALEXA FLUOR 488

동의어(들):

Tubulin beta-4, Tubulin beta-III, tubulin, beta 3, tubulin, beta, 4

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR 488
Clone:
polyclonal
Application:
ICC, IHC
Citations:
21
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biological source

rabbit

Quality Segment

conjugate

ALEXA FLUOR 488

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)

General description

50 kDa calculated
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

Immunogen

Synthetic linear peptide corresponding to human Beta III Tubulin.

Application

Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Biochem/physiol Actions

This antibody recognizes Beta III Tubulin.

Physical form

Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat E18 cortex cells
Evaluated by Immunocytochemistry in rat E18 cortex cells.

Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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