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Merck

AB5543

Anti-MAP2 Antibody

CHEMICON®, chicken polyclonal

동의어(들):

Anti-MAP-2, Anti-MAP2A, Anti-MAP2B, Anti-MAP2C

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
rat
Application:
immunocytochemistry
immunohistochemistry
western blot
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Citations:
84
Uniprot accession no.:
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제품 이름

Anti-MAP2 Antibody, Chemicon®, from chicken

biological source

chicken

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

rat ... Map2(25595)

Analysis Note

Control
Positive = cerebral cortex. Negative = liver or kidney.

Application

Anti-MAP2 Antibody is an antibody against MAP2 for use in IC, IH & WB.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism
Western blot: 1:5,000-1:10,000 using ECL. Recognizes a doublet of ~280 kDa and a doublet of ~70kDa.

Immunohistochemistry on frozen tissue sections. Suggested fixative is 4% paraformaldehyde (1-10 minutes) followed by 5 minutes in -20°C methanol.

Immunocytochemistry: 1:5,000-1:10,000 on cells in tissue culture fixed for 1-10 minutes in 10% formalin followed by five minutes in -20°C methanol.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Microtubule Associated Protein 2 (MAP2). It is expected that the antibody will react with all mammals.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Recognizes a doublet of ~280 kDa and a doublet of ~70kDa

Immunogen

Purified bovine brain MAP2

Physical form

Ammonium Sulfate Precipitation
Format: Purified
Purified chicken IgY. Liquid in PBS containing 5 mM sodium azide.

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine.
Acton, D; Miles, GB
Testing null
Yumiko V Taguchi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(40), 9617-9631 (2017-08-30)
Glucocerebrosidase 1 (GBA) mutations responsible for Gaucher disease (GD) are the most common genetic risk factor for Parkinson's disease (PD). Although the genetic link between GD and PD is well established, the underlying molecular mechanism(s) are not well understood. We
Riikka H Hämäläinen et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(38), E3622-E3630 (2013-09-05)
Mitochondrial DNA (mtDNA) mutations manifest with vast clinical heterogeneity. The molecular basis of this variability is mostly unknown because the lack of model systems has hampered mechanistic studies. We generated induced pluripotent stem cells from patients carrying the most common
M Catarina Silva et al.
eLife, 8 (2019-03-26)
Tauopathies are neurodegenerative diseases characterized by aberrant forms of tau protein accumulation leading to neuronal death in focal brain areas. Positron emission tomography (PET) tracers that bind to pathological tau are used in diagnosis, but there are no current therapies
Ester Orav et al.
eNeuro, 4(3) (2017-07-07)
Kainate-type glutamate receptors (KARs) are highly expressed in the developing brain, where they are tonically activated to modulate synaptic transmission, network excitability and synaptogenesis. NETO proteins are auxiliary subunits that regulate biophysical properties of KARs; however, their functions in the

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