Anti-GRIP-1 Antibody, CT

Glutamate receptor interacting protein-1 (GRIP-1) is a multi-PDZ domain scaffold protein and a member of the steroid receptor coactivator (SRC) family of proteins. GRIP-1 interacts and maneuvers kinesin heavy chains to dendrites by acting as the power source for AMPA receptors. During initial stages of embryonic development, GRIP-1 is essential for typical cell-matrix interactions.

~121 kDa observed

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of rat GRIP-1.

Detect GRIP-1 using this Anti-GRIP-1 Antibody, C-terminus validated for use in WB, IP, IH(P).

Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated GRIP-1 from rat brain cytosol tissue lysate.

Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected GRIP-1 in rat brain cells.

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

This antibody recognizes GRIP-1 at the C-terminus.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Rat brain cytosol tissue lysate

Evaluated by Western Blot in rat brain cytosol tissue lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected GRIP-1 on 10 µg of rat brain cytosol tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: 06-986

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