Anti-CD34 Class III Antibody, clone 581

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Study of the Class III CD34 epitope by FACS

Optimal working dilutions must be determined by the end user.

This Anti-CD34 Antibody, Class III, clone 581 is validated for use in FC for the detection of CD34 Class III.

Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.

The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.

Format: Purified

Protein G affinity chromatography. The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

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