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Merck

MABN738

Anti-OCT6 Antibody, clone KT110

clone KT110, from mouse

동의어(들):

POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
KT110, monoclonal
Application:
EMSA, IHC, WB
Citations:
8
기술 서비스
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도움 문의
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도움 문의

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

KT110, monoclonal

species reactivity

mouse, human

technique(s)

electrophoretic mobility shift assay: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SLC22A16(85413)

General description

Octamer-binding protein 6 (Oct-6) is also called POU domain, class 3, transcription factor 1 (Pou3f1), Octamer-binding transcription factor 6 (OTF-6) and POU domain transcription factor SCIP. Oct-6 is a transcription factor that specifically binds to the (5′-ATTTGCAT-3′) octamer motif. Oct-6 has been implicated in early embryogenesis, neurogenesis, keratinocyte differentiation and myelination in the peripheral nervous system.
~50 kDa observed

Immunogen

Recombinant protein corresponding to mouse OCT6.

Application

Anti-OCT6 Antibody, clone KT110 is a highly specific mouse monoclonal antibody, that targets Oct-6 & has been tested in western blotting, IHC & Electrophoretic Mobility Shift Assay.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected OCT6 in mouse embryonic brain (D15.5) tissue.
Electophoretic Mobility Shift Assay (EMSA) Analysis: A representative lot detected SphK1 in nuclear extracts from RT4 Schwannoma or primay rat Shcwann cells (Prof. D. Meijer, Erasmus University Medical Center, Rotterdam.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

Physical form

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1κ in buffer containing PBS and 0.9% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in H9 human embreyonic stem cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected OCT6 in 10 µg of H9 human embreyonic stem cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABN1060

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

저장 등급

12 - Non Combustible Liquids


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Vittoria Dickinson Bocchi et al.
Science (New York, N.Y.), 372(6542) (2021-05-08)
Deciphering how the human striatum develops is necessary for understanding the diseases that affect this region. To decode the transcriptional modules that regulate this structure during development, we compiled a catalog of 1116 long intergenic noncoding RNAs (lincRNAs) identified de
Michel Fries et al.
Cell reports, 42(8), 112985-112985 (2023-08-17)
The balance of contralateral and ipsilateral retinogeniculate projections is critical for binocular vision, but the transcriptional programs regulating this process remain ill defined. Here we show that the Pou class homeobox protein POU3F1 is expressed in nascent mouse contralateral retinal
Joshua Po Han Wu et al.
Frontiers in molecular neuroscience, 15, 921901-921901 (2022-08-09)
The cerebellar nuclear (CN) neurons are a molecularly heterogeneous population whose specification into the different cerebellar nuclei is defined by the expression of varying sets of transcription factors. Here, we present a novel molecular marker, Pou3f1, that delineates specific sets
Masaki Kinoshita et al.
Cell stem cell, 28(3), 453-471 (2020-12-04)
Pluripotent cells emerge as a naive founder population in the blastocyst, acquire capacity for germline and soma formation, and then undergo lineage priming. Mouse embryonic stem cells (ESCs) and epiblast-derived stem cells (EpiSCs) represent the initial naive and final primed
Sophie M Morgani et al.
Methods in molecular biology (Clifton, N.J.), 2214, 41-58 (2020-09-19)
Pluripotent stem cells (PSCs) are the in vitro counterpart of the pluripotent epiblast of the mammalian embryo with the capacity to generate all cell types of the adult organism. During development, the three definitive germ layers are specified and simultaneously

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MABN73804053252929953

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