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제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
41104923
NACRES:
NB.13
eCl@ss:
32039006
Material:
PTFE plate (PTFE), white plate
Sterility:
non-sterile
Manufacturer/tradename:
MultiScreen®
Packaging:
pkg of 1 collection plate
material
PTFE plate (PTFE), white plate
sterility
non-sterile
usage
Manual
packaging
pkg of 1 collection plate
manufacturer/tradename
MultiScreen®
technique(s)
parallel artificial membrane permeation assay (PAMPA): suitable
plate size
96 wells
compatibility
manifold only
General description
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
Application
Non-Sterile, reusable, sturdy device made of PTFE, acceptor plate for PAMPA assays, 1 plate
Research Category
Nucleic acid|Protein
Nucleic acid|Protein
Physical form
Color Code:Not Applicable
Other Notes
Automation Compatible:Yes
Legal Information
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
문서
Development of an automation-compatible, high-throughput method for the determination of drug concentrations in serum or plasma samples.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| MSSACCEPT0R | 04053252267864 |