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Merck

C9231

Carbenicillin disodium

meets USP testing specifications

동의어(들):

Carbenicillin disodium salt, α-Carboxybenzylpenicillin disodium salt

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C17H16N2Na2O6S
CAS 번호:
4800-94-6
Molecular Weight:
422.36
UNSPSC Code:
51102829
NACRES:
NA.76
PubChem Substance ID:
24893142
EC Number:
225-360-8
Beilstein/REAXYS Number:
5722128
MDL number:
MFCD00077683

주요 문서

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InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

agency

USP/NF, meets USP testing specifications

form

solid

solubility

H2O: 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

pharmaceutical (small molecule)

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

Quality Level

200

관련 카테고리

General description

Chemical structure: β-lactam

Application

Used for selection of ampr transformed cells. Used to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

Biochem/physiol Actions

Mode of Action: Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.


Antimicrobial spectrum: Active against Gram-positive and Gram-negative bacteria

Analysis Note

Stable at 37 °C for 3 days

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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시험 성적서(COA)

Lot/Batch Number
0000511778
0000511778
0000504450
0000504449
0000504449

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문서 라이브러리 방문

Yasser M Abdelrahman et al.
Nucleic acids research, 39(5), 1843-1854 (2010-11-06)
Chlamydia trachomatis is an obligate intracellular bacterium that exhibits a unique biphasic developmental cycle that can be disrupted by growth in the presence of IFN-γ and β-lactams, giving rise to an abnormal growth state termed persistence. Here we have examined
Brigitte K Ziervogel et al.
Structure (London, England : 1993), 21(1), 76-87 (2012-12-04)
The structure of OmpF porin in complex with three common antibiotics (zwitterionic ampicillin, anionic ertapenem, and di-anionic carbenicillin) was determined using X-ray crystallography. The three antibiotics are found to bind within the extracellular and periplasmic pore vestibules, away from the
Jun Yang et al.
Plant science : an international journal of experimental plant biology, 181(6), 701-711 (2011-10-01)
Efficient Agrobacterium tumefaciens-mediated transformation was developed using embryogenic suspension cell cultures of elite sweet potato (Ipomoea batatas [L.] Lam.) cultivars, including Ayamurasaki, Sushu2, Sushu9, Sushu11, Wanshu1, Xushu18 and Xushu22. Embryogenic suspension cultures were established in LCP medium using embryogenic calli
Lintao Zeng et al.
Chemical communications (Cambridge, England), 46(14), 2435-2437 (2010-04-10)
A fluorescent probe (QA) based on quinine bearing two quaternary ammonium groups and a long hydrophobic chain was synthesized, and it showed highly selective recognition of carbenicillin (a typical beta-lactam antibiotic) in 100% aqueous solution via concerted interactions.
Catherine Kaminski et al.
Critical care (London, England), 15(2), R112-R112 (2011-04-13)
Although Pseudomonas aeruginosa is a leading pathogen responsible for ventilator-associated pneumonia (VAP), the excess in mortality associated with multi-resistance in patients with P. aeruginosa VAP (PA-VAP), taking into account confounders such as treatment adequacy and prior length of stay in
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