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Merck

PMB3001

L-Glutamine

99-101%, ISOM8, suitable for cell culture, from non-animal source

동의어(들):

L-Glutamine, (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide, (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H2NCOCH2CH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
146.14
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1723797
NACRES:
NA.28
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biological source

non-animal source

Quality Segment

agency

meets USP, meets requirements for USP (testing)

product line

ISOM8

assay

99-101%

form

powder

optical activity

[α]/D 31-35°, c = 2 M in HCl (10 in 2M HCl), [α]/D 6.3-7.3° in water (4 in water)

technique(s)

cell culture | mammalian: suitable

color

white

mp

185 °C (dec.) (lit.), 185 °C

solubility

water: 25 mg/mL

functional group

amide

storage temp.

room temp

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

General description

L-Glutamine is a conditionally essential amino acid. It is the most abundant free amino acid in mammalian plasma and intracellular fluids, playing a central role in nitrogen metabolism and biosynthetic pathways. Structurally, L-Glutamine is the γ-amide of glutamic acid, featuring an amide group in its side chain that enables it to function as a major nitrogen donor in a variety of metabolic reactions.

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Features and Benefits

Features:

1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
3. M-Clarity Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/m-clarity-program
4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
  • Site quality assessment
  • ISO 9001 certificate
  • Detailed product specifications
  • Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)


Benefits:


1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Legal Information

ISOM8 is a trademark of Sigma-Aldrich Co. LLC
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany


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저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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시험 성적서(COA)

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