A4161
Bovine Serum Albumin
lyophilized powder, essentially globulin free, BioReagent, suitable for cell culture
동의어(들):
Albumin bovine serum, BSA, Bovine albumin
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Biological source:
bovine
Assay:
≥99%
Form:
lyophilized powder
Technique(s):
cell culture | mammalian: suitable
Impurities:
essentially globulin free
제품 이름
Bovine Serum Albumin, lyophilized powder, essentially globulin free, BioReagent, suitable for cell culture
biological source
bovine
product line
BioReagent
assay
≥99%
form
lyophilized powder
mol wt
~66 kDa
purified by
cold ethanol and heatshock fractionation
packaging
poly bottle of
origin
USA origin
technique(s)
cell culture | mammalian: suitable
impurities
essentially globulin free
pH
7
solubility
water: soluble (50 mg/ml)
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
bovine ... ALB(280717)
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Features and Benefits
- Tested for use in cell culture
- Essentially globulin free
Preparation Note
Purified by a combination of heat shock and ethanol fractionation
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.
Biochem/physiol Actions
Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Guido Bolognesi et al.
Nature communications, 9(1), 1882-1882 (2018-05-16)
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Mark A Petersen et al.
Neuron, 96(5), 1003-1012 (2017-11-07)
Blood-brain barrier (BBB) disruption alters the composition of the brain microenvironment by allowing blood proteins into the CNS. However, whether blood-derived molecules serve as extrinsic inhibitors of remyelination is unknown. Here we show that the coagulation factor fibrinogen activates the
Aseel El Hajj et al.
PloS one, 14(6), e0218812-e0218812 (2019-06-25)
The regulation of cholesterol, an essential brain lipid, ensures proper neuronal development and function, as demonstrated by links between perturbations of cholesterol metabolism and neurodegenerative diseases, including Alzheimer's disease. The central nervous system (CNS) acquires cholesterol via de novo synthesis
Melisa Herrero et al.
Neuromolecular medicine, 21(3), 303-313 (2019-05-28)
Vanishing white matter (VWM) disease (OMIM#306896) is an autosomal recessive neurodegenerative leukodystrophy caused by hypomorphic mutations in any of the five genes encoding the subunits of eukaryotic translation initiation factor 2B (eIF2B). The disease is manifested by loss of cerebral
Silvana Konermann et al.
Cell, 173(3), 665-676 (2018-03-20)
Class 2 CRISPR-Cas systems endow microbes with diverse mechanisms for adaptive immunity. Here, we analyzed prokaryotic genome and metagenome sequences to identify an uncharacterized family of RNA-guided, RNA-targeting CRISPR systems that we classify as type VI-D. Biochemical characterization and protein
문서
Explore serum albumin's role in serum-free cell culture systems for biomanufacturing.
관련 콘텐츠
Learn about bovine serum albumin (BSA) structure, molecular weight, function, solubility, how BSA is made, purification methods, applications and purchasing.
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