콘텐츠로 건너뛰기
Merck

A5268

Alcian Blue 8GX

powder

동의어(들):

Alcian Blue, Ingrain Blue 1

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C56H68Cl4CuN16S4
CAS 번호:
33864-99-2
Molecular Weight:
1298.86
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24890962
EC Number:
251-705-7
Colour Index Number:
74240
MDL number:
MFCD00010720

주요 문서

모든 문서 보기
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의

InChI key

CKLBXIYTBHXJEH-UHFFFAOYSA-J

InChI

1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4

SMILES string

[Cl-].[Cl-].[Cl-].[Cl-].CN(C)C(\SCc1ccc2c3nc(nc4n5[Cu]n6c(nc7nc(nc5c8cc(CS\C(N(C)C)=[N+](\C)C)ccc48)c9ccc(CS\C(N(C)C)=[N+](\C)C)cc79)c%10ccc(CS\C(N(C)C)=[N+](\C)C)cc%10c6n3)c2c1)=[N+](/C)C

form

powder

composition

Dye content, 45-65%

technique(s)

microbe id | staining: suitable

color

blue

solubility

H2O: 1 mg/mL

εmax

425 at 615-630 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

General description

Alcian Blue 8GX, also known as Ingrain Blue 1, is a basic copper phthalocyanine dye whose copper content imparts a blue color. It is tetravalent, cationic, and water-soluble in nature. It forms salt linkages with the acid groups of acid mucopolysaccharides.

Application

  • Alcian Blue 8GX has been used for the staining and precipitation of glycosaminoglycans and as a heteroglycan stain for neutral, sulfated, and phosphated mucopolysaccharides and glycosaminoglycans in tissues such as cartilage and extracellular matrices.
  • It has been employed in the in vivo visualization of intravascular Bonghan ducts and corpuscles in murine models.
  • It has been used to develop a novel histochemical staining method to assess multiple respiratory parameters in various species.

Biochem/physiol Actions

The Alcian blue staining is easily combined with the Periodic acid-Schiff (PAS) reaction. In the tissue, acid mucosubstances are stained selectively and nuclear fast red is commonly used as counterstain. In combination with the PAS reaction, non-substituted polysaccharides, neutral mucopolysaccharides, muco- and glycoproteins, and glycol- and phospholipids can be visualized in addition. An Acetic acid-Alcian blue solution is used for the staining, whereby carboxylated and sulfatic proteoglycans are selectively stained when a pH of 2.5 is applied. The differentiation between carboxyl and sulfate groups is only possible at pH 1.

Features and Benefits

Desired staining patterns can be obtained by manipulating pH and salt concentrations.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000418088
0000418088
0000413285
0000413285
0000421283

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

In vivo visualization of Bonghan ducts inside blood vessels of mice by using an Alcian blue staining method
Yoo, et al.
Indian Journal of Experimental Biology, 46 (2008)
Histotechnology: A Self-instructional Text (3rd ed.)
Freida L. Carson & Christa Hladik
Histotechnology: A Self Instructional Text, 4th Edition (2009)
The quantitative determination of glycosaminoglycans in urine with Alcian Blue 8GX.
Whiteman P
The Biochemical Journal, 131, 351-357 (1973)
Replacement of the medial tibial plateau by a metallic implant in a goat model.
Custers RJ, et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 28, 429-435 (2010)
Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage.
Mastbergen SC, et al.
Rheumatology (Oxford, England), 41, 801-808 (2002)
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.