D4902

Dexamethasone

Name: Dexamethasone
Brand: SIGMA

powder, BioReagent, suitable for cell culture, ≥97%

동의어(들):

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₂₂H₂₉FO₅

CAS 번호:

50-02-2

Molecular Weight:

392.46

UNSPSC Code:

12352209

NACRES:

NA.75

PubChem Substance ID:

24893906

EC Number:

200-003-9

Beilstein/REAXYS Number:

2066651

MDL number:

MFCD00064136

Biological source:

synthetic

Form:

powder

Assay:

≥97%

주요 문서

모든 문서 보기

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제품 이름

Dexamethasone, powder, BioReagent, suitable for cell culture, ≥97%

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

biological source

synthetic

product line

BioReagent

assay

≥97%

form

powder

potency

4-500 ng/mL

technique(s)

cell culture | mammalian: suitable
single cell analysis: suitable

mp

262-264 °C (lit.)

solubility

methanol: 25 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)
rat ... Ar(24208), Nr3c1(24413), Tnf(24835)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

Application

Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation and gene expression.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

It is poorly metabolized in the body and has great affinity and bioavailability.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Physical form

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Preparation Note

To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.

pictograms

GHS08

signalword

Danger

hcodes

H360FD

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Lot/Batch Number

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문서 라이브러리 방문

Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes

Kimberly A Chapman

Molecular Genetics and Metabolism, 117, 355-362 (2016)

Isolation of Mesenchymal Stem Cells from Human Deciduous Teeth Pulp.

Tsai Aileen

BioMed Research International (2017)

Multipotency and cardiomyogenic potential of human adipose-derived stem cells from epicardium, pericardium, and omentum

Wojciech Wystrychowski

Stem Cell Research & Therapy (2015)

The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

Agnes

Molecular and Cellular Endocrinology, 335(1), 2-13 (2011)

The Effect of Turmeric (Curcuma longa) Extract on the Functionality of the Solute Carrier Protein 22 A4 (SLC22A4) and Interleukin-10 (IL-10) Variants Associated with Inflammatory Bowel Disease

Mark J Cann

Nutrients, 6(10) (2014)

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프로토콜

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Dexamethasone

powder, BioReagent, suitable for cell culture, ≥97%

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

InChI key

InChI

SMILES string

biological source

product line

assay

form

potency

technique(s)

mp

solubility

shipped in

storage temp.

Quality Level

Gene Information

관련 카테고리

설명

Application

Biochem/physiol Actions

Packaging

Physical form

Preparation Note

안전성 정보

pictograms

signalword

hcodes

pcodes

Hazard Classifications

저장 등급

wgk

flash_point_f

flash_point_c

ppe

문서

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