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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
CAS 번호:
Molecular Weight:
280.45
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12352211
EC Number:
200-470-9
MDL number:
Beilstein/REAXYS Number:
1727101
biological source
plant (Safflower oil)
product line
BioReagent
assay
≥98%
form
liquid
technique(s)
cell culture | mammalian: suitable
refractive index
n20/D 1.466 (lit.)
bp
229-230 °C/16 mmHg (lit.)
mp
−5 °C (lit.)
solubility
NaOH: 1 M, ethanol: soluble
density
0.902 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
InChI key
OYHQOLUKZRVURQ-HZJYTTRNSA-N
Gene Information
human ... SOAT1(6646), SOAT2(8435)
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General description
Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.
Application
Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.
Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .
Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.
Packaging
Sealed ampule.
저장 등급
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Intramyocardial adipose-derived stem cell transplantation increases pericardial fat with recovery of myocardial function after acute myocardial infarction
Kim JH, et al.
PLoS ONE, 11(6), e0158067-e0158067 (2016)
Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production
Cytotechnology, 112(6), 51-56 (1994)
Differentiation and characterization of rhesus monkey atrial and ventricular cardiomyocytes from induced pluripotent stem cells
Zhang X, et al.
Stem Cell Research, 20(6), 21-29 (2017)
Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells
Pei F, et al.
Stem Cell Research, 19(6), 94-103 (2017)
Linoleic acid: a nutritional quandary
Jandacek RJ
Healthcare (Basel, Switzerland) , 5(2), 25-25 (2017)
문서
Lipid Induced Insulin Resistance
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