L4402
Lysostaphin from Staphylococcus staphylolyticus
BioUltra, ≥97% (SDS-PAGE), Protein 40-60 % by biuret, ≥2,000 units/mg protein
동의어(들):
Glycyl-glycine Endopeptidase
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥2,000 units/mg protein
Assay:
≥97% (SDS-PAGE)
Biological source:
bacterial (Staphylococcus sp.)
Concentration:
40—60% protein
biological source
bacterial (Staphylococcus sp.)
Quality Level
product line
BioUltra
assay
≥97% (SDS-PAGE)
form
lyophilized powder
specific activity
≥2,000 units/mg protein
mol wt
25 kDa
composition
Protein, 40-60% biuret
concentration
40—60% protein
technique(s)
cell based assay: suitable
suitability
suitable for cell lysis
antibiotic activity spectrum
Gram-positive bacteria
application(s)
diagnostic assay manufacturing
mode of action
cell wall synthesis | interferes
storage temp.
−20°C
General description
Chemical structure: peptide
Package size based on protein content
Biochem/physiol Actions
Lysostaphin is a zinc endopeptidase with a molecular weight of approximately 25 kDa. Because lysostaphin cleaves the polyglycine cross-links in the peptidoglycan layer of the cell wall of Staphylococcus species it has been found useful for cell lysis and also as a potential anti-microbial therapeutic.
pH Optimum for activity: ~7.5
pH Optimum for activity: ~7.5
Physical form
Contains potassium phosphate buffer salts and sodium chloride
Preparation Note
Affinity purified
Other Notes
One unit will reduce the turbidity (A620) of a suspension of Staphylococcus aureus cells from 0.250 to 0.125 in 10 min at pH 7.5 at 37 °C in a 6.0 ml reaction mixture.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
관련 콘텐츠
QC Methods
Instructions
Johnny Gutierrez et al.
Open forum infectious diseases, 6(4), ofz090-ofz090 (2019-04-27)
Staphylococcus aureus (SA) bacteremia often requires a long treatment duration with antibiotics to prevent relapse due to the ability of SA to establish reservoirs of infection in sites such as heart and bone. These metastatic sites of infection cannot be
R Satishkumar et al.
Nanotechnology, 22(50), 505103-505103 (2011-11-24)
The objective of this paper was to study the effect of antibody-directed targeting of S. aureus by comparing the activities of lysostaphin conjugated to biodegradable polylactide nanoparticles (NPs) in the presence and in the absence of co-immobilized anti-S. aureus antibody.
Thomas S Lawson et al.
Journal of clinical laboratory analysis, 25(5), 359-365 (2011-09-16)
Aspects of the fluorescence in situ hybridization (FISH) method for the detection of clinically important bacteria, such as Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli, were investigated for optimization. Various approaches to optimizing the FISH procedure were taken and different