L9043
Lysostaphin from Staphylococcus simulans
recombinant, expressed in E. coli, lyophilized powder
동의어(들):
Glycyl-glycine Endopeptidase
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제품정보 (DICE 배송 시 비용 별도)
CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥3000 unit/mg solid
Assay:
≥90% (HPLC)
Biological source:
bacterial
Recombinant:
expressed in E. coli
biological source
bacterial
Quality Segment
recombinant
expressed in E. coli
assay
≥90% (HPLC)
form
lyophilized powder
specific activity
≥3000 unit/mg solid
technique(s)
molecular cloning: suitable
suitability
suitable for sequence analysis test
application(s)
life science and biopharma
shipped in
dry ice
storage temp.
−20°C
General description
Lysostaphin, a zinc metalloenzyme, is mainly secreted as a proenzyme. It acts as an anti-staphylococcal agent and is highly stable at pH 4 and 5°C.
Application
Lysostaphin from Staphylococcus simulans has been used in a study to assess molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus. It has also been used in a study to investigate the sequence analysis of a Staphylococcus aureus gene encoding a peptidoglycan hydrolase activity.
Biochem/physiol Actions
A protein complex with highly specific lytic activity against Staphylococcus species, including Staphylococcus aureus.
Lysostaphin possesses a lytic action against Staphylococcus aureus, which is used to treat antibiotic-resistant staphylococcal infections. It has the properties of enzymes, such as glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acetyl muramyl-L-alanine amidase. Lysostaphin is also used as a preservative in food industry and in clinical labs for rapid screening.
The antimicrobial activity of lysostaphin, a metalloendopeptidase expressed by Staphylococcus simulans, is enhanced by binding to the C′ terminus of the membrane-associated Trap protein of Staphylococcus aureus.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)