R7017
Resazurin sodium salt
powder, BioReagent
동의어(들):
7-Hydroxy-3H-phenoxazin-3-one-10-oxide sodium salt
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H6NNaO4
CAS 번호:
Molecular Weight:
251.17
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
263-718-5
Beilstein/REAXYS Number:
3794971
MDL number:
InChI key
IVGPGQSSDLDOLH-UHFFFAOYSA-M
InChI
1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1
SMILES string
[Na+].[O-]c1ccc2c(OC3=CC(=O)C=CC3=[N+]2[O-])c1
product line
BioReagent
form
powder
composition
Dye content, ~80%
pH
3.8-6.5, orange to violet
solubility
H2O: soluble
λmax
600 nm
Quality Level
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Application
For the measurement of metabolic activity and proliferation of living cells. The bioreduction of the dye reduces the amount of the oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).
Resazurin sodium salt has been used in viability assay:
- to measure cell viability of A. fumigatus
- to assess cell proliferation
- to determine A. fumigatus viability in high-throughput screenings of microbial natural extracts
Biochem/physiol Actions
Resazurin is a blue, non-fluorescent dye originally used to test milk/biological fluids for bacterial and yeast contamination. It is also useful in sperm viability and semen quality test. Resazurin is applicable in cytotoxicity determination.
ppe
dust mask type N95 (US), Eyeshields, Gloves
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010)
Valiante V, et al.
Antimicrobial agents and chemotherapy, 59(9), 5145-5153 (2015)
Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb
Chao DT, et al.
Journal of Cancer Research and Clinical Oncology, 139, 315?325-315?325 (2012)
Sugandha Bhatia et al.
Journal of clinical medicine, 8(6) (2019-06-27)
Dynamic interconversions between transitional epithelial and mesenchymal states underpin the epithelial mesenchymal plasticity (EMP) seen in some carcinoma cell systems. We have delineated epithelial and mesenchymal subpopulations existing within the PMC42-LA breast cancer cell line by their EpCAM expression. These
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
O Brien J, et al.
European Journal of Biochemistry, 267(17), 5421-5426 (2000)
Amir Kumar Singh et al.
Nature communications, 9(1), 4515-4515 (2018-10-31)
Dysregulated ROR-γt-mediated IL-17 transcription is central to the pathogenesis of several inflammatory disorders, yet the molecular mechanisms that govern the transcription factor activity of ROR-γt in the regulation of IL-17 are not fully defined. Here we show that SUMO-conjugating enzyme
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