U6381
Uridine
≥99%, synthetic (organic), powder
동의어(들):
1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C9H12N2O6
CAS 번호:
Molecular Weight:
244.20
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
200-407-5
MDL number:
Beilstein/REAXYS Number:
754902
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: 0.1 M, clear, colorless
제품 이름
Uridine, BioUltra, ≥99%
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
biological source
synthetic (organic)
product line
BioUltra
assay
≥99%
form
powder
impurities
≤0.016% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.2%
Quality Level
Gene Information
mouse ... Uck1(22245)
solubility
H2O: 0.1 M, clear, colorless
cation traces
Al: ≤0.0005%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.003%, K: ≤0.005%, Mg: ≤0.003%, NH4+: ≤0.15%, Na: ≤0.02%, Pb: ≤0.005%, Zn: ≤0.0005%
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General description
Uridine is a pyrimidine nucleoside which is crucial for the synthesis of RNA and membranes. It helps in normal cell function and growth by forming pyrimidine nucleotide -lipid conjugates.
Application
Uridine has been used to study the functional complementation of nucleoside hydrolase from a protozoan parasite and mammalian uridine phosphorylase on URH1 (uridine hydrolase) of Saccharomyces cerevisiae.
It has been used to check the effect of chronic uridine application on liver metabolism in mice.
It has been used to check the effect of chronic uridine application on liver metabolism in mice.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
Urasaki Y, et al.
PLoS ONE, 11, e0146994-e0146994 (2016)
Purinergic and Pyrimidinergic Signalling: Molecular, Nervous and Urogenitary System Function
Handbook of Experimental Pharmacology (2013)
Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase.
Mitterbauer R, et al.
Applied and Environmental Microbiology, 68, 1336-1343 (2002)
Qi Qiu et al.
Nature methods, 17(10), 991-1001 (2020-09-02)
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and pre-existing mRNAs from the same
Ian E Crandall et al.
Journal of medicinal chemistry, 56(6), 2348-2358 (2013-02-16)
Resistance by Plasmodium falciparum to almost all clinically used antimalarial drugs requires the development of new classes of antimalarials. 6-Iodouridine (15), a novel and potent inhibitor of orotidine 5'-monophosphate decarboxylase (ODCase), exhibited efficacy in a mouse model infected by P.
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