A Range of Columns for Reliable Solid-Phase Extraction
LiChrolut® columns are designed for reliable and rapid solid-phase extraction (SPE). This is achieved by using strong but reversible interactions between the analyte and the surface of the stationary phase. A variety of surface modifications allow non-polar extraction (LiChrolut® RP-18 and RP- 18 endcapped), polar extraction (LiChrolut® Si and LiChrolut® CN), cation exchange extraction (LiChrolut® SCX), mixed mode extraction (LiChrolut® TSC), and non-polar extraction on a polymer phase (LiChrolut® EN). The latter is especially suitable for the extraction of pesticides and phenols in water, or drugs in body fluids.
LiChrolut® sorbents offer excellent batch-to-batch consistency. This is due to stringent testing of raw materials and continuous quality controls of the final product. The optimized, validated and certificated production of the sorbents also ensures a high degree of purity and uniformity. The multi-stage purification procedures performed on LiChrolut® materials are particularly valuable for trace analysis. The proportion of elutable components is negligibly small, resulting in purer extracts. As all stationary phases are monitored using the most sensitive analytical methods, very narrow set tolerances can be adhered to.
The optimal extraction method depends on the analyte’s structure, solubility, polarity and lipophilic properties (distribution coefficients). The guide below will help you choose the most favorable LiChrolut® column for your application.
|Sorbent type||High porosity synthetic silica gel particles||Ethyl vinyl benzene divinyl benzene polymer (orange), irregular shaped|
|Particle size||40-63 μm||40-120 µm|
|Pore size||60 Å||-|
|Pore volume||-||0.75 mL/g|
|Specific surface area||~ 600 m2/g||1,200 m²/g (according to BET)|
|pH stability||pH 2-8||pH 1-13|
Wide spectra of chemically modified
Si 60 high purity, CN, RP-18e, RP-18,
SCX (strong cation exchanger),TSC (Tox Screening Cation)
500 mg caffeine/g sorbent (model substance for polar analytes)500 mg diisodecylphtalate DIDP/g sorbent (model substance for nonpolar analytes)
|Sorbent type||Magnesia-loaded silica gel|
|Particle size||150-250 μm|