C5041
6-Carboxyfluorescein diacetate
~95% purity (HPLC), powder
Synonym(s):
6-CFDA, 6-Carboxy-di-O-acetylfluorescein
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About This Item
Empirical Formula (Hill Notation):
C25H16O9
CAS Number:
Molecular Weight:
460.39
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
67043
Product Name
6-Carboxyfluorescein diacetate, ≥95% (HPLC)
assay
≥95% (HPLC)
form
powder
color
white to yellow
solubility
chloroform/ethanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1
InChI
1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
InChI key
QMOGCCYGOPYYNT-UHFFFAOYSA-N
Application
6-Carboxyfluorescein diacetate has been used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin.
Fluorescent wavelengths λex 492nm; λemm 517nm in 0.1M Tris, pH 8.0.
Fluorescent wavelengths λex 492nm; λemm 517nm in 0.1M Tris, pH 8.0.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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G Ricci et al.
Human reproduction (Oxford, England), 17(10), 2665-2672 (2002-09-28)
Apoptosis plays an important role in regulating spermatogenesis. However, the biological significance of apoptosis in ejaculated sperm is not yet clear. This study set out to investigate how apoptosis correlates with semen quality and the presence of seminal leukocytes. Fifty-seven
Gopal Patel et al.
Frontiers in bioengineering and biotechnology, 8, 631-631 (2020-07-03)
The present study explores the influence of mycophenolic acid (MPA) in combination therapy with quercetin (QC) (impeding MPA metabolic rate) delivered using the liposomal nanoparticles (LNPs). Mycophenolic acid liposome nanoparticles (MPA-LNPs) and quercetin liposome nanoparticles (QC-LNPs) were individually prepared and
S Capellero et al.
Scientific reports, 10(1), 6478-6478 (2020-04-17)
Despite improvements in surgery and medical treatments, epithelial ovarian cancer (EOC) remains the most lethal gynaecological malignancy. Aim of this study is to investigate the preclinical immunotherapy activity of cytokine-induced killer lymphocytes (CIK) against epithelial ovarian cancers, focusing on platinum-resistant