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About This Item
Linear Formula:
[Ru(CO)3Cl2]2
CAS Number:
Molecular Weight:
512.01
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
MDL number:
InChI
1S/6CO.4ClH.2Ru/c6*1-2;;;;;;/h;;;;;;4*1H;;/q;;;;;;;;;;2*+2/p-4
SMILES string
[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].Cl[Ru]Cl.Cl[Ru]Cl
InChI key
JYHHJVKGDCZCCL-UHFFFAOYSA-J
reaction suitability
core: ruthenium, reagent type: catalyst
Quality Level
Application
Carbon monoxide-releasing molecule used for pharamological studies including:
Used as a CO donor for reactive oxygen species mediated bacterial killing
- Enhancement of coagulation and attenuation of vulnerability to fibrinolysis
- Investigations of P2X4 as a possible target
- Possible modification of thrombus growth or disintegration
- Enhances fibrinogen as a substrate for thrombin
- Regulation of ion transport by gasotransmitters
Used as a CO donor for reactive oxygen species mediated bacterial killing
Tricarbonyldichlororuthenium(II) dimer can be used in the deuteration reaction for labeling secondary amines. It can also be used for the synthesis of racemization catalysts by reacting with cyclopenta[l]phenanthrenyl and cyclopenta[a]acenaphthylenyl ligands.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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One-step exchange-labelling of piperidines, piperazines and dialkylamines with deuterium oxide: catalysis by various ruthenium complexes.
Alexakis E, et al.
Tetrahedron Letters, 46(25), 4291-4293 (2005)
Vance G Nielsen et al.
International journal of molecular sciences, 21(6) (2020-03-22)
Using thrombelastography to gain mechanistic insights, recent investigations have identified enzymes and compounds in Naja and Crotalus species' neurotoxic venoms that are anticoagulant in nature. The neurotoxic venoms of the four extant species of Dendroaspis (the Black and green mambas)
Vance G Nielsen et al.
Basic & clinical pharmacology & toxicology, 120(2), 207-212 (2016-08-23)
Since the introduction of antivenom administration over a century ago to treat venomous snake bite, it has been the most effective therapy for saving life and limb. However, this treatment is not always effective and not without potential life-threatening side
Michał Majewski et al.
Antioxidants (Basel, Switzerland), 9(2) (2020-02-08)
Alcoholic leaf and petal fractions of Taraxacum officinale (dandelion) were previously demonstrated to exert in vitro antioxidant and antithrombotic activities in blood plasma and platelets. Eight-week-old male Wistar rats (n = 6) were supplemented for four weeks with dandelion fractions
Cyclopenta [l] phenanthrenyl and Cyclopenta [a] acenaphthylenyl Half-Sandwich Complexes of Ruthenium as Racemization Catalysts for Secondary Alcohols.
Mavrynsky D, et al.
Organometallics, 28(2), 598-605 (2008)
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