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Merck

420247

(+)-Borneol

97%

Synonym(s):

endo-(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):
C10H18O
CAS Number:
464-43-7
Molecular Weight:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
24866321
EC Number:
207-352-6
Beilstein/REAXYS Number:
2038056
MDL number:
MFCD00066427
Assay:
97%
Form:
solid

Key Documents

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InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

assay

97%

form

solid

optical activity

[α]20/D +36°, c = 5 in ethanol

Quality Level

200

Gene Information

human ... UGT1A4(54657)

mp

206-209 °C (lit.)

functional group

hydroxyl

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General description

(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.

Application

(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Flame
GHS02

signalword

Warning

hcodes

H228

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000506330
0000506330
0000479716
0000479716
0000204322

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jing-yi Zhao et al.
Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)
Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to
Xiao Song et al.
Die Pharmazie, 67(10), 848-851 (2012-11-10)
The aim of this work was to study the in situ and in vivo nasal absorption of borneol. A novel single pass in situ nasal perfusion technique was applied to examine the rate and extent of nasal absorption of borneol
Fatiha El Babili et al.
Journal of medicinal food, 15(7), 671-676 (2012-05-23)
The volatile components from Croton campestris root bark were localized by an anatomical study and analyzed by gas chromatography-mass spectrometry for the first time. The roots of this plant showed secretory cells. These volatile constituents, isolated from the dichloromethane extract
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