755842
6-Maleimidohexanoic acid
90% (GC)
Synonym(s):
2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid, 6-Maleimide hexanoic acid, MCA, Maleimidocaproic acid, 6-Maleimidocaproic acid, N-Maleoyl-6-aminocaproic acid, N-(5-Carboxypentyl)maleimide
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About This Item
Empirical Formula (Hill Notation):
C10H13NO4
CAS Number:
Molecular Weight:
211.21
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1532405
Quality Level
assay
90% (GC)
form
powder
mp
87-92 °C
storage temp.
2-8°C
SMILES string
OC(=O)CCCCCN1C(=O)C=CC1=O
InChI
1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)
InChI key
WOJKKJKETHYEAC-UHFFFAOYSA-N
Application
Intermediate for ester and amide linked maleimide monomers
Probe for thiol groups (SH-groups) in membrane proteins.
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signalword
Warning
hcodes
Hazard Classifications
Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
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D B R K Gupta Udatha et al.
Journal of structural biology, 190(3), 314-327 (2015-04-25)
The catalytic residues in carbohydrate esterase enzyme families constitute a highly conserved triad: serine, histidine and aspartic acid. This catalytic triad is generally located in a very sharp turn of the protein backbone structure, called the nucleophilic elbow and identified
You-Jun Li et al.
Oncotarget, 6(35), 36943-36954 (2015-10-16)
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) encodes a tumor suppressor gene implicated in the growth of various tumor types including breast cancer. We previously demonstrated that recombinant adenovirus-mediated mda-7/IL-24 expression in the mammary glands of carcinogen-treated (methylnitrosourea, MNU) rats suppressed mammary
Joanna M Wardlaw et al.
International journal of stroke : official journal of the International Stroke Society, 10(6), 956-968 (2013-01-23)
Intravenous thrombolysis with recombinant tissue Plasminogen Activator improves outcomes in patients treated early after stroke but at the risk of causing intracranial hemorrhage. Restricting recombinant tissue Plasminogen Activator use to patients with evidence of still salvageable tissue, or with definite