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About This Item
agency
reag. Ph. Eur.
Quality Level
vapor density
1.11 (vs air)
vapor pressure
128 hPa ( 20 °C), 410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)
product line
LiChrosolv®
grade
gradient grade (for liquid chromatography), gradient grade
assay
≥99.9% (GC)
autoignition temp.
725 °F
expl. lim.
36 %
greener alternative product characteristics
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
impurities
≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.02% Water
transmittance
210 nm, ≥20%, 220 nm, ≥60%, 230 nm, ≥75%, 235 nm, ≥83%, 250 nm, ≥95%, 260 nm, 98%
refractive index
n20/D 1.329 (lit.), n/D (n20/D 1.329)(lit.)
bp
64.7 °C (lit.)
mp
−98 °C (lit.)
transition temp
flash point 9.7 °C
density
0.791 g/mL at 25 °C (lit.)
absorption
≤0.01 at 260 nm, ≤0.02 at 250 nm, ≤0.07 at 240 nm, ≤0.13 at 230 nm, ≤0.170 at 225 nm, ≤0.30 at 220 nm, ≤0.70 at 210 nm
UV absorption
λ: 225 nm Amax: ≤0.170
SMILES string
CO
suitability
suitable for HPLC
application(s)
(HPLC)
greener alternative category
InChI
1S/CH4O/c1-2/h2H,1H3
InChI key
OKKJLVBELUTLKV-UHFFFAOYSA-N
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General description
- Derived from renewable feedstocks with bio-carbon content certification
- Similar chromatographic resolution, reproducibility, and baseline stability
- Drop-in replacement: no method redevelopment required
Application
- Reversed-Phase HPLC: Commonly used as a mobile phase component for the separation of a wide range of compounds, including pharmaceuticals, environmental pollutants, and biomolecules.
- Gradient Elution: Ideal for gradient elution techniques, enhancing the resolution, and separation efficiency of complex mixtures.
- Pharmaceutical Analysis: Frequently employed in the analysis of active pharmaceutical ingredients (APIs) and their impurities, ensuring compliance with regulatory standards.
- Biological Sample Analysis: Used for the analysis of proteins, peptides, and metabolites in biological samples, facilitating accurate quantification and identification.
- Environmental Monitoring: Applied in the HPLC analysis of environmental samples to detect and quantify contaminants in water, soil, and air.
Features and Benefits
- High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
- Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
- Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
- Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility, and confidence in analytical results.
Analysis Note
- Evaporation Number: 1.9
- Identity (IR): conforms
- Evaporation residue: ≤ 2.0 mg/l
- Color: ≤ 10
- Density (d 20 °C/20 °C): 0.791 - 0.793
- Gradient grade (at 235 nm): ≤ 2.0 mAU
- Gradient grade (at 254 nm): ≤ 1.0 mAU
- Filtered by 0.2 µm filter. Suitable for UPLC / UHPLC /Ultra HPLC - instruments.
- Conforms to Methanol R1 and R2 according to Reag. Ph Eur; conforms to the requirements of ACS for liquid chromatography suitability.
Other Notes
This high-quality HPLC-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab. Know more about our data matrix code-labeled HPLC-grade solvents.
LiChrosolv® bio-based solvents are derived from renewable feedstocks and verified through bio-carbon content certification. They provide comparable chromatographic performance to conventional solvents—same resolution, reproducibility, and baseline stability—and function as drop-in replacements requiring no method redevelopment
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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