8.04518
N-Hydroxysuccinimide
≥99.0% (acidimetric), for peptide synthesis
Synonym(s):
N-Hydroxysuccinimide, 1-Hydroxy-2,5-pyrrolidinedione
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About This Item
Empirical Formula (Hill Notation):
C4H5NO3
CAS Number:
Molecular Weight:
115.09
UNSPSC Code:
12352115
EC Index Number:
228-001-3
NACRES:
NA.22
MDL number:
Product Name
N-Hydroxysuccinimide, for synthesis
Quality Level
assay
≥99.0% (acidimetric)
form
crystals
reaction suitability
reaction type: Addition Reactions
pH
5-7 (20 °C, 50 g/L in H2O)
mp
93-100 °C
application(s)
peptide synthesis
SMILES string
N1(C(=O)CCC1=O)O
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
InChI key
NQTADLQHYWFPDB-UHFFFAOYSA-N
Application
- Direct Cα-heteroarylation of structurally diverse ethers: This study showcases a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction, expanding the utility of NHS in organic synthesis. (Liu et al., 2017).
Analysis Note
Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 95 °C
Melting range (upper value): ≤ 100 °C
Identity (IR): passes test
Melting range (lower value): ≥ 95 °C
Melting range (upper value): ≤ 100 °C
Identity (IR): passes test
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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