07579
Synperonic® F 108
surfactant, non-ionic
Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)
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About This Item
CAS Number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.22
MDL number:
Quality Level
impurities
≤0.5% water
mp
56-61 °C
hydroxyl value
6‑9 mg KOH/g
application(s)
detection
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
General description
Synperonic F-108 is a polyoxyethylene-polyoxypropylene block copolymer. It has two hydrophilic groups that are attached to a central hydrophobic group that self-assembles in an aqueous solution into clusters known as micelles. This water-soluble surfactant is used as effective emulsification and solubilizing agent in a wide range of applications.
Application
Synperonic® F 108 may be used as an adjuvant for lentiviral (LV) transduction. It possesses higher (LV) transduction efficiency than polybrene.
Legal Information
Synperonic is a registered trademark of Croda International PLC
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Ines Höfig et al.
The journal of gene medicine, 14(8), 549-560 (2012-08-14)
Although lentiviral transduction methods are widely used, their broader application is dependent upon the optimization of lentiviral transduction efficiency for a broad range of cell types. In the present study, we focus on the evaluation of two chemical classes with
Bishnubrata Patra et al.
Scientific reports, 6, 21061-21061 (2016-02-16)
Three-dimensional (3D) tumor spheroid possesses great potential as an in vitro model to improve predictive capacity for pre-clinical drug testing. In this paper, we combine advantages of flow cytometry and microfluidics to perform drug testing and analysis on a large
Feby Wijaya Pratiwi et al.
Biomedicines, 9(1) (2020-12-31)
Mesoporous silica nanoparticles (MSNs) have emerged as a prominent nanomedicine platform, especially for tumor-related nanocarrier systems. However, there is increasing concern about the ability of nanoparticles (NPs) to penetrate solid tumors, resulting in compromised antitumor efficacy. Because the physicochemical properties