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About This Item
Linear Formula:
MnCl2 · 4H2O
CAS Number:
Molecular Weight:
197.91
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-869-6
MDL number:
Assay:
≥99%
Form:
powder
InChI key
CNFDGXZLMLFIJV-UHFFFAOYSA-L
InChI
1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
SMILES string
Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
product line
ReagentPlus®
assay
≥99%
form
powder
pH
3.5-6 (25 °C, 50 g/L)
mp
58 °C (lit.)
Quality Level
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General description
Manganese(II) chloride tetrahydrate is the tetrahydrate form of manganese(II) chloride. It is used in the preparation of manganese-based hybrid compounds.
Application
Manganese(II) chloride tetrahydrate can be used:
- As a promoter to synthesize dihydropyrimidin-2(1H)-ones by the condensation of aldehyde, β-dicarbonyl compounds, and urea under microwave conditions.
- As a catalyst to synthesize dihydro-2-oxypyrrole derivatives via one-pot four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde, and amines.
- To synthesize active manganese oxide with potential application as an oxidant in organic synthesis.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
target_organs
Brain
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 2
flash_point_f
does not flash
flash_point_c
does not flash
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Seong-Uk Jin et al.
Magnetic resonance imaging, 31(7), 1143-1149 (2013-05-11)
The cochlear plays a vital role in the sense and sensitivity of hearing; however, there is currently a lack of knowledge regarding the relationships between mechanical transduction of sound at different intensities and frequencies in the cochlear and the neurochemical
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Anne Bertrand et al.
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
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