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Merck

B6125

N-Benzoyl-L-tyrosine ethyl ester

Synonym(s):

BTEE

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NHCOC6H5)CO2C2H5
CAS Number:
Molecular Weight:
313.35
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
222-469-2
MDL number:
Beilstein/REAXYS Number:
2223819
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InChI key

SRLROPAFMUDDRC-INIZCTEOSA-N

InChI

1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m0/s1

SMILES string

CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2ccccc2

form

powder

mp

118-121 °C (lit.)

storage temp.

−20°C

Quality Level

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Application

N-Benzoyl-L-tyrosine ethyl ester has been used for measuring chymotrypsin activity.

General description

N-Benzoyl-L-tyrosine ethyl ester (BTEE) is a substrate which is completely resistant to trypsin and is required for the assay of chymotrypsin.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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F Chen et al.
Biochemical and biophysical research communications, 214(3), 985-992 (1995-09-25)
In this report, we demonstrate that NF-kappa B, a ubiquitous transcription factor, plays an essential role in silica-induced inflammatory mediator production in the mouse macrophage cell line RAW 264.7. Compared to the effect of lipopolysaccharide (LPS), silica mediated a stronger
Guilbault GG
Enzymatic Methods of Analysis: International Series of Monographs in Analytical Chemistry (201)
C J Lo et al.
The Journal of surgical research, 69(2), 408-412 (1997-05-01)
Nuclear factor kappa B (NF kappa B) is an important transcriptional activator protein and is a crucial component of the host's response to infection. The activation of NF kappa B is correlated with the phosphorylation of inhibitory kappa B (I
J Kantorski et al.
Journal of bioluminescence and chemiluminescence, 7(1), 37-45 (1992-01-01)
We have studied an indirect role of serine and thiol proteases in the activation of human neutrophils in vitro. Stimulation was evaluated using a chemiluminescence (CL) generation system. Receptor-dependent and receptor-independent stimuli were studied, e.g. opsonized zymosan, formyl-methionyl-leucyl-phenylalanine, platelet activating
Hydrolysis of polyesters by serine proteases.
Lim HA
Biotechnology Letters, 27, 459-464 (2005)

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