Anti-Connexin-32 (106-124) antibody produced in rabbit

Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.

synthetic human connexin-32 peptide (amino acids 106-124).

Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.

Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:

• western blotting
• immunofluorescence
• immunohistology

Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.

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