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D1538

Piperazine diacrylamide

Name: Piperazine diacrylamide
Brand: SIGMA

For acrylamide gel electrophoresis

Synonym(s):

1,4-Bis(acryloyl)piperazine, 1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂O₂

CAS Number:

6342-17-2

Molecular Weight:

194.23

UNSPSC Code:

12352200

NACRES:

NA.52

PubChem Substance ID:

24893477

MDL number:

MFCD00077661

Beilstein/REAXYS Number:

745431

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Properties

Quality Level

200

grade

Molecular Biology

product line

BioReagent

form

powder

technique(s)

electrophoresis: suitable

mp

91.5-93.5 °C (lit.)

storage temp.

room temp

SMILES string

C=CC(=O)N1CCN(CC1)C(=O)C=C

InChI

1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2

InChI key

YERHJBPPDGHCRJ-UHFFFAOYSA-N

Description

General description

1,4-Bis(acryloyl)piperazine is a reagent that can be substituted for bis-acrylamide in the preparation of polyacrylamide gels.

Application

Suitable for preparation of gels for PAGE, IEF, 2D electrophoresis and protein sequencing.

Features and Benefits

increases the gel strength and resolution
reduces background for silver background
can be substituted for bisacrylamide without changing polymerization protocol

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites.

Ronaldo de Carvalho Augusto et al.

PLoS neglected tropical diseases, 11(7), e0005789-e0005789 (2017-07-29)

Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly

Fractionation techniques in a hydro-organic environment. II. Acryloyl-morpholine polymers as a matrix for electrophoresis in hydro-organic solvents.

G Artoni et al.

Analytical biochemistry, 137(2), 420-428 (1984-03-01)

The properties of gels prepared either from acryloyl-morpholine (ACM) or from its mixtures with acrylamide and crosslinked either with bisacrylylpiperazine or with methylenebisacrylamide have been described. ACM-containing gels are compatible with organic solvents. If polymerized in water and dried, they

An update on conformation sensitive gel electrophoresis.

Arupa Ganguly

Human mutation, 19(4), 334-342 (2002-04-05)

Conformation-sensitive gel electrophoresis (CSGE) was developed as a method of heteroduplex analysis to screen large multi-exon genes for sequence variation. The novelty of the method was in the use of a non-proprietary acrylamide gel matrix that used 1,4-bis (acrolyl) piperazine

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