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Merck

L2376

Linolenic acid

≥99%

Synonym(s):

α-Lnn, cis,cis,cis-9,12,15-Octadecatrienoic acid

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About This Item

Linear Formula:
CH3(CH2CH=CH)3(CH2)7CO2H
CAS Number:
463-40-1
Molecular Weight:
278.43
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
24896311
EC Number:
207-334-8
Beilstein/REAXYS Number:
1727693
MDL number:
MFCD00065720
Assay:
≥99%
Quality level:
200

Key Documents

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InChI key

DTOSIQBPPRVQHS-PDBXOOCHSA-N

InChI

1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9-

SMILES string

CC/C=C\C/C=C\C/C=C\CCCCCCCC(O)=O

assay

≥99%

refractive index

n20/D 1.480 (lit.)

bp

230-232 °C/1 mmHg (lit.)

mp

-11 °C (lit.)

density

0.914 g/mL at 25 °C (lit.)

lipid type

omega FAs

storage temp.

−20°C

Quality Level

200

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Application

Linolenic acid has been used:
  • to assess the total antioxidative activity of serum and bacteria
  • in palleroni chamber assay
  • to prepare free fatty acid mixture

Biochem/physiol Actions

An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. Conversion is greater in women than men, and conversely, β-oxidation metabolism is greater in men than women.
Linolenic acid is involved in the formation of highly unsaturated fatty acid. It is essential for the development of skin, blood and neural cells. Linolenic acid is also associated with the organization of lipid membranes of neural synapses, pigment epithelial cells of retina and myocardial cells. It plays an important role in brain development and prostaglandin synthesis. Deficiency of essential fatty acid is related to skin disorders and growth retardation.

General description

Linolenic acid is an essential fatty acid, which is not produced in the body. Plants and fishes are rich sources of linolenic acid.

Packaging

Sealed ampule

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000528322
0000528322
0000511545
0000511545
0000511546

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