T1502
Triethanolamine hydrochloride
≥99.5% (titration)
Synonym(s):
2,2′,2′′-Nitrilotriethanol hydrochloride, Tris(2-hydroxyethyl)amine hydrochloride
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About This Item
Linear Formula:
(HOCH2CH2)3N · HCl
CAS Number:
Molecular Weight:
185.65
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
211-284-2
Beilstein/REAXYS Number:
3909940
MDL number:
Quality Level
assay
≥99.5% (titration)
form
crystalline powder
useful pH range
7.3-8.3
pKa (25 °C)
7.8
mp
177-179 °C (lit.)
solubility
water: 0.333 g/mL, clear, colorless
application(s)
diagnostic assay manufacturing
SMILES string
Cl.OCCN(CCO)CCO
InChI
1S/C6H15NO3.ClH/c8-4-1-7(2-5-9)3-6-10;/h8-10H,1-6H2;1H
InChI key
HHLJUSLZGFYWKW-UHFFFAOYSA-N
General description
Triethanolamine (TEA) belongs to the family of ethanolamine. It includes the properties of both amines and alcohols. Addition of TEA to an acidic buffer facilitates the determination of fluoride in inorganic orthophosphates by using a fluoride-selective electrode.
Application
Triethanolamine hydrochloride has been used:
- in the preparation of triethanolamine buffer
- in rinsing the digested sections, prepared for in situ hybridization
- as a component of solution A to prepare TA-complement haemolysis buffer (TA-CHB)
Biochem/physiol Actions
Triethanolamine hydrochloride acts as a surfactant or pH adjuster. It is also used as an emulsifier in cosmetics and several topical medications.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Fiume M, et al.
International Journal of Toxicology, 32(3\_suppl), 59S-83S (2013)
Optimal conditions for the kinetic assay of serum glutamate dehydrogenase activity at 37? C
Ellis G and Goldberg DM
Clinical Chemistry, 18(6), 523-527 (1972)
Toxicology of mono-, di-, and triethanolamine
Reviews of Environmental Contamination and Toxicology, 1-86 (1997)