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Merck

T9753

D-Tryptophan

≥98.0% (HPLC)

Synonym(s):

(R)-2-Amino-3-(3-indolyl)propionic acid, D-α-Amino-3-indolepropionic acid

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
153-94-6
Molecular Weight:
204.23
NACRES:
NA.32
PubChem Substance ID:
24900598
UNSPSC Code:
12352103
EC Number:
205-819-9
MDL number:
MFCD00005647
Beilstein/REAXYS Number:
86198

Key Documents

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Product Name

D-Tryptophan, ≥98.0% (HPLC)

InChI key

QIVBCDIJIAJPQS-SECBINFHSA-N

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1

SMILES string

N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

biological source

synthetic (organic)

assay

≥98.0% (HPLC)

form

powder

technique(s)

cell culture | embryo: suitable
cell culture | mammalian: suitable

color

white to off-white

mp

282-285 °C (dec.) (lit.)

Quality Level

200

Gene Information

human ... GRINA(2907)
mouse ... GRINA(66168)
rat ... GRINA(266668)

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Application

D-Tryptophan has been used to study its efficacy on dispersing biofilm in dental unit waterlines (DUWLs) in vitro.
D-Tryptophan can be used for Human embryonic kidney cell (HEK-293, ATCC: CRL-1573) culture.The product is a sweetener used to study the release of incretins from enteroendocrine cells triggered by sugar but not by sweeteners.

Biochem/physiol Actions

Low level of D-tryptophan is capable of preventing the growth of an L-tryptophan-requiring mutant of the E. coli.

General description

Tryptophan is one of the essential and standard amino acids present in the body. It is used by the cells to produce proteins.

Other Notes

Unnatural isomer of tryptophan.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW0243
MKCT7977
MKCT0095
MKCS3587
MKCR3947

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C F Morris et al.
Plant physiology, 88(2), 435-440 (1988-10-01)
An endogenous germination inhibitor(s) in wheat (Triticum aestivum L.) grain has been implicated in seed dormancy and germination, but its identity and mode of action have not been elucidated. We isolated and identified an endogenous germination inhibitor in white wheat
Application of D-Amino Acids as Biofilm Dispersing Agent in Dental Unit Waterlines
Ampornaramveth RS, et al.
International journal of dentistry, 2018(4954) (2018)
Substances Involved in Neurotransmission
Nutritional and Herbal Therapies for Children and Adolescents, 71-99 (2010)
Action of D-Tryptophan on E. coli
Hatanaka M
Nature, 204(4954), 202-203 (1964)
Fangjie Zheng et al.
Electrophoresis, 40(16-17), 2218-2226 (2019-04-27)
Establishing a simple and accurate method for Hg2+ detection is of great importance for the environment and human health. In this work, platinum nanoparticles (Pt NPs) with different capped agents and morphologies were synthesized. It was found that Pt NPs
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