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Merck

I3875

Indoxyl sulfate potassium salt

Synonym(s):

Potassium 3-indoxyl sulfate, Urinary indican

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About This Item

Linear Formula:
C8H6NO4SK
CAS Number:
Molecular Weight:
251.30
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-145-5
Beilstein/REAXYS Number:
3921324
MDL number:
Assay:
> 98 %
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assay

> 98 %

Quality Level

mp

165 °C (dec.) (lit.)

solubility

water: soluble

storage temp.

−20°C

SMILES string

[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12

InChI

1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1

InChI key

MDAWATNFDJIBBD-UHFFFAOYSA-M

General description

Indoxyl sulfate potassium salt is derived from indoxyl sulfate by replacing the hydrogen ion with a potassium cation. Potassium indoxyl sulfate is used as a reagent for the detection and determination of hydrogen peroxide.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Indoxyl-sulfate activation of the AhR-NF-$\kappa$B pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve
Candellier, et al.
Journal of Molecular and Cellular Cardiology, 179, 18-29 (2023)
Bummei Sato et al.
The American journal of cardiology, 111(5), 712-716 (2012-12-12)
The prognosis of patients with diastolic heart failure (HF) is as poor as that of patients with systolic HF. Greater chronic kidney disease-associated mortality occurs in patients with left ventricular (LV) diastolic HF than in those with systolic HF. Indoxyl
Binding affinity and capacity for the uremic toxin indoxyl sulfate
Devine, et al.
Toxins, 6, 416-429 (2014)