AB9348
Anti-Myelin Basic Protein Antibody
CHEMICON®, chicken polyclonal
Synonym(s):
Anti-C76307, Anti-Hmbpr, Anti-R75289, Anti-golli-mbp, Anti-jve, Anti-mld, Anti-shi
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Product Name
Anti-Myelin Basic Protein Antibody, Chemicon®, from chicken
biological source
chicken
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MBP(4155)
mouse ... Mbp(17196)
Application
Anti-Myelin Basic Protein Antibody detects level of Myelin Basic Protein & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues.
Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neurochemistry & Neurotrophins
Neuronal & Glial Markers
Neurochemistry & Neurotrophins
Biochem/physiol Actions
Recognizes Myelin Basic Protein (MBP).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide from human/mouse MBP.
Physical form
Affinity purified chicken IgY. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that you store the antibody in the dark.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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José Javier Miguel-Hidalgo et al.
Chronic stress (Thousand Oaks, Calif.), 2 (2019-02-19)
Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder. In rat models of stress (major depressive disorder risk factor) astrocyte gap junction protein connexin 43 (Cx43) is reduced in the prelimbic cortex. Astrocyte
Caroline Guglielmetti et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(33), E6982-E6991 (2017-08-02)
Proinflammatory mononuclear phagocytes (MPs) play a crucial role in the progression of multiple sclerosis (MS) and other neurodegenerative diseases. Despite advances in neuroimaging, there are currently limited available methods enabling noninvasive detection of MPs in vivo. Interestingly, upon activation and
C Guglielmetti et al.
NeuroImage, 125, 363-377 (2015-11-04)
Although MRI is the gold standard for the diagnosis and monitoring of multiple sclerosis (MS), current conventional MRI techniques often fail to detect cortical alterations and provide little information about gliosis, axonal damage and myelin status of lesioned areas. Diffusion
Elodie Martin et al.
Brain plasticity (Amsterdam, Netherlands), 5(2), 123-133 (2020-12-08)
Microglia are the resident macrophages of the central nervous system (CNS). In multiple sclerosis (MS) and related experimental models, microglia have either a pro-inflammatory or a pro-regenerative/pro-remyelinating function. Inhibition of Bruton's tyrosine kinase (BTK), a member of the Tec family
Debbie Le Blon et al.
Journal of neuroinflammation, 13(1), 288-288 (2016-11-11)
Promoting the neuroprotective and repair-inducing effector functions of microglia and macrophages, by means of M2 polarisation or alternative activation, is expected to become a new therapeutic approach for central nervous system (CNS) disorders in which detrimental pro-inflammatory microglia and/or macrophages
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB9348 | 04053252508929 |
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