Skip to Content
Merck

46648

Praziquantel

VETRANAL®, analytical standard

Synonym(s):

2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C19H24N2O2
CAS Number:
55268-74-1
Molecular Weight:
312.41
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756613
EC Number:
259-559-6
Beilstein/REAXYS Number:
761557
MDL number:
MFCD00058531

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Praziquantel, VETRANAL®, analytical standard

InChI key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

InChI

1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

SMILES string

O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

parasites

application(s)

clinical testing

format

neat

mode of action

cell membrane | interferes

storage temp.

2-8°C

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

PZQ may be used as a reference standard for the determination for PZQ in:
  • Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.
  • Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.
  • Tablet formulations by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: quinolone
Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN5934
BCCM3808
BCCG8493
BCCD7937
BCCB5592

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Study of praziquantel phytoremediation and transformation and its removal in constructed wetland.
Marsik P, et al.
Journal of Hazardous Materials, 323, 394-399 (2017)
Analysis of anthelmintics in surface water by ultra high performance liquid chromatography coupled to quadrupole linear ion trap tandem mass spectrometry.
Zrncic M, et al.
Chemosphere, 99, 224-232 (2014)
Development and validation of a dissolution test method for albendazole and praziquantel in their combined dosage form.
Vignaduzzo S, et al.
Journal of the Brazilian Chemical Society, 26(4), 729-735 (2015)
Chromatographic separation of racemic praziquantel and its residual determination in perch by LC-MS/MS.
He L, et al.
Talanta, 174, 380-386 (2017)
Shona Wilson et al.
PLoS neglected tropical diseases, 7(3), e2149-e2149 (2013-04-05)
IgE specific to worm antigen (SWA) and pre-treatment eosinophil number, are associated with human immunity to re-infection with schistosomes after chemotherapeutic treatment. Treatment significantly elevates circulating IL-5 24-hr post-treatment of Schistosoma mansoni. Here we investigate if praziquantel treatment of human
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service