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Merck

67126

Oxolinic acid

analytical standard

Synonym(s):

5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C13H11NO5
CAS Number:
14698-29-4
Molecular Weight:
261.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329760414
EC Number:
238-750-8
Beilstein/REAXYS Number:
620635
MDL number:
MFCD00056775

Key Documents

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grade

analytical standard

Quality Level

100

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12

InChI

1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

InChI key

KYGZCKSPAKDVKC-UHFFFAOYSA-N

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Related Categories

General description

Chemical structure: quinolone

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9008
BCCL8192
BCCK2451
BCCK5787
BCCH5554

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R A Palominos et al.
Journal of hazardous materials, 158(2-3), 460-464 (2008-04-11)
This work studied the photocatalysed oxidation of the antibiotic oxolinic acid (OA) in an annular reactor operated with immobilized TiO(2) on sintered glass cylinders (SGC). Experiments were carried out in 1l solution of OA (18 mg l(-1)) at pH 9
Hong-Thih Lai et al.
Chemosphere, 75(4), 462-468 (2009-02-24)
Oxolinic acid (OA) and flumequine (FLU) are two of the quinolone antibiotics (QAs) that are widely used in aquaculture. The purpose of this study was to understand the fates of OA and FLU in waters and sediment slurries from aquaculture
gyrA and parC associated with quinolone resistance in Vibrio anguillarum.
C Rodkhum et al.
Journal of fish diseases, 31(5), 395-399 (2008-04-11)
Xiuhong Wang et al.
The Journal of antimicrobial chemotherapy, 65(3), 520-524 (2010-01-14)
Quinolone-mediated death of Escherichia coli has been proposed to occur by two pathways. One is blocked by inhibitors of protein synthesis; the other is not. It is currently unknown how these two pathways fit with the recent observation that hydroxyl
Kalliopi C Skyrianou et al.
Journal of inorganic biochemistry, 105(10), 1273-1285 (2011-08-09)
The nickel(II) complexes with the quinolone antibacterial agents oxolinic acid, flumequine, enrofloxacin and sparfloxacin in the presence of the N,N'-donor heterocyclic ligand 2,2'-bipyridylamine have been synthesized and characterized. The quinolones act as bidentate ligands coordinated to Ni(II) ion through the
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